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Revive

The potentials of CBD

Nanogel Enhanced
Herbal-Complex, Unleashing Skin’s Healing power

HyaSphere Revive: Advanced Wound Healing and Scar Care

Experience the healing power of our Nanogel Enhanced Herbal-Complex. This innovative formula unleashes your skin’s natural ability to rejuvenate and heal, providing a revitalizing touch of nature in every application.
 
A powerful active ingredient designed to support all stages of wound healing and scar care. It combines a proven herbal complex with enhanced stability and improved skin penetration with the unique HyaSphereX nanogel delivery system.

 

7 functions
in
1 ingredient

01

Delivery System

Enhance the efficacy with automatically encapsulate, easy, single step, low setup cost

02

Moisturizing

Hydrate the skin, prevent water loss better than hyaluronic acid

03

Soothing

Calm irritate and sensitive skin by reducing COX-2 inflammatory marker

04

Whitening

Reduce number of melanocyte

05

Anti-wrinkle

Reduce wrinkle by inhibit collagenase enzyme, anti-oxidant, prevent cell damage from UV-A exposure.

06

Wound healing

Accelerate wound closure

07

Increase stability

Prevent degradation and color change of vitamin, protein, herbal extracts

How does it work

HyaSphereX, where innovation meets transformation. We’re dedicated to elevating the efficacy and stability of bioactive molecules through a multifaceted approach.

Promotes efficient uptake by skin cells, maximizing bioavailability and results.

HyaSphereX employs a proprietary mechanism to significantly increase the solubility of bioactive molecules. This breakthrough ensures that these compounds dissolve more readily, paving the way for improved formulations and enhanced therapeutic outcomes.

Facilitates deeper penetration into the skin layers for enhanced efficacy.

Enhance Penetration of Bioactives

Mechanism of Action: HyaSphereX enhances enetration of active ingredients through transcellular, intercellular, and follicular route.

HyaSphereX deposits and hydrates epidermis using hydrophobic part that is available on the particle’s surface as a flexible anchor and extremely hydrophilic hyaluronic acid backbone as super-humectant, respectively. 

Through the moisturized skin, the very hygroelastic particle of HyaSphereX could squeeze itself with the help of moisture in the extracellular matrix (ECM).

In viable skin layers, underneath stratum corneum, HyaSphereX could be uptaken by keratinocytes and fibroblast derived cells through transcellular and paracellular transportation.

Unique hydrophobic part within swollen HyaSphereX induces the expansion of the very porous particles of HyaSphereX in the deeper skin temperature making hydration even more effective as it excels the accessibility of hydrogen bonds between water and hyaluronic acid backbone.

Prevent Degradation of Bioactives

We proposed the possible mechanisms of how HyaSphereX help increase stability of active ingredient and the formulation.

Both water-soluble and oil-soluble active ingredients can be bonded (non-covalent) with hydrophilic/hydrophobic part of HyaSphereX, possibly hydroxyl groups for hydrophilic polymer/ hydrophobic interaction with hydrophobic crosslink sites. So the degradation is hindered.

Inside the particle is gel matrix meaning that the viscosity is high and molecular motion of water is limited. So it slower the degradation of any molecules.

Enhanced Solubility

HyaSphereX employs a proprietary mechanism to significantly increase the solubility of bioactive molecules. This breakthrough ensures that these compounds dissolve more readily, paving the way for improved formulations and enhanced therapeutic outcomes.

Increase Penetration

Our technology goes beyond conventional methods by enhancing the penetration capabilities of bioactive molecules. This means that these compounds can reach their target sites more efficiently, maximizing their impact and potential benefits.

Optimize Cellular Uptake

Promotes efficient uptake by skin cells, maximizing bioavailability and results.

Hydration

HyaSphereX deposits and hydrates epidermis using hydrophobic part that is available on the particle’s surface as a flexible anchor and extremely hydrophilic hyaluronic acid backbone as super-humectant, respectively.

Passive Penetration

Through the moisturized skin, the very hygroelastic particle of HyaSphereX could squeeze itself with the help of moisture in the extracellular matrix (ECM).

Active Cellular Uptake

In viable skin layers, underneath stratum corneum, HyaSphereX could be uptaken by keratinocytes and fibroblast derived cells through transcellular and paracellular transportation.

Hyper-moisturization

Unique hydrophobic part within swollen HyaSphereX induces the expansion of the very porous particles of HyaSphereX in the deeper skin temperature making hydration even more effective as it excels the accessibility of hydrogen bonds between water and hyaluronic acid backbone.

NON-COVALENT INTERACTION

Both water-soluble and oil-soluble active ingredients can be bonded (non-covalent) with hydrophilic/hydrophobic part of HyaSphereX, possibly hydroxyl groups for hydrophilic polymer/ hydrophobic interaction with hydrophobic crosslink sites. So the degradation is hindered.

MINIMIZING THE MOLECULAR MOTION BY SPHERICAL GEL MATRIX

Insdie the particle is gel matrix meaning that the viscosity is high and molecular motion of water is limited. So it slower the degradation of any molecules.

HOW DOES IT WORK

HyaSphereX incorporates multifunctional features, including enhanced solubility, increased penetration, and optimized cellular uptake.

ENHANCE PENETRATION OF BIOACTIVE

HyaSphereX enhances penetration of both water-soluble and oil-soluble active ingredients through transcellular, intercellular, and follicular routes.

Prevent Degradation of Bioactive

HyaSphereX, through its unique, flexible 3D nanogel structure, help increase stability of active ingredients and the formulations.

How does it work

HyaSphereX, where innovation meets transformation. We’re dedicated to elevating the efficacy and stability of bioactive molecules through a multifaceted approach.
slide1

Promotes efficient uptake by skin cells, maximizing bioavailability and results.

Enhances the solubility of active ingredients, ensuring optimal formulation.

Facilitates deeper penetration into the skin layers for enhanced efficacy.

HyaSphereX deposits and hydrates epidermis using hydrophobic part that is available on the particle’s surface as a flexible anchor and extremely hydrophilic hyaluronic acid backbone as super-humectant, respectively.

Through the moisturized skin, the very hygroelastic particle of HyaSphereX could squeeze itself with the help of moisture in the extracellular matrix (ECM).

In viable skin layers, underneath stratum corneum, HyaSphereX could be uptaken by keratinocytes and fibroblast derived cells through transcellular and paracellular transportation.

Unique hydrophobic part within swollen HyaSphereX induces the expansion of the very porous particles of HyaSphereX in the deeper skin temperature making hydration even more effective as it excels the accessibility of hydrogen bonds between water and hyaluronic acid backbone.

Both water-soluble and oil-soluble active ingredients can be bonded (non-covalent) with hydrophilic/hydrophobic part of HyaSphereX, possibly hydroxyl groups for hydrophilic polymer/ hydrophobic interaction with hydrophobic crosslink sites. So the degradation is hindered.

Inside the particle is gel matrix meaning that the viscosity is high and molecular motion of water is limited. So it slower the degradation of any molecules.

Enhanced Solubility

HyaSphereX employs a proprietary mechanism to significantly increase the solubility of bioactive molecules. This breakthrough ensures that these compounds dissolve more readily, paving the way for improved formulations and enhanced therapeutic outcomes.

Increase Penetration

Our technology goes beyond conventional methods by enhancing the penetration capabilities of bioactive molecules. This means that these compounds can reach their target sites more efficiently, maximizing their impact and potential benefits.

Optimize Cellular Uptake

HyaSphereX facilitates increased cellular uptake of bioactive molecules, ensuring a more efficient and effective interaction with cells. This mechanism enhances the bioavailability of the compounds, amplifying their positive effects within the biological system.

Hydration

HyaSphereX deposits and hydrates epidermis using hydrophobic part that is available on the particle’s surface as a flexible anchor and extremely hydrophilic hyaluronic acid backbone as super-humectant, respectively.

Passive Penetration

Through the moisturized skin, the very hygroelastic particle of HyaSphereX could squeeze itself with the help of moisture in the extracellular matrix (ECM).

Active Cellular Uptake

In viable skin layers, underneath stratum corneum, HyaSphereX could be uptaken by keratinocytes and fibroblast derived cells through transcellular and paracellular transportation.

Hyper-moisturization

Unique hydrophobic part within swollen HyaSphereX induces the expansion of the very porous particles of HyaSphereX in the deeper skin temperature making hydration even more effective as it excels the accessibility of hydrogen bonds between water and hyaluronic acid backbone.

NON-COVALENT INTERACTION

Both water-soluble and oil-soluble active ingredients can be bonded (non-covalent) with hydrophilic/hydrophobic part of HyaSphereX, possibly hydroxyl groups for hydrophilic polymer/ hydrophobic interaction with hydrophobic crosslink sites. So the degradation is hindered.

MINIMIZING THE MOLECULAR MOTION BY SPHERICAL GEL MATRIX

Insdie the particle is gel matrix meaning that the viscosity is high and molecular motion of water is limited. So it slower the degradation of any molecules.

Enhance Penetration of Bioactive

HyaSphereX enhances penetration of both water-soluble and oil-soluble active ingredients through transcellular, intercellular, and follicular route.

Prevent Degradation of Bioactive

HyaSphereX, through its unique, flexible 3D nanogel structure, help increase stability of active ingredients and the formulations.

Prevent Degradation of Bioactive

HyaSphereX, through its unique, flexible 3D nanogel structure, help increase stability of active ingredients and the formulations.

Microplastic free

ECOCERT COSMOS Approved

International patented

99.95% Natural origin ISO 16128

HYN Technology Delivery System

Preservative free

Vegan

Halal

Biodegradable

China CosIng

Discover the wonders

Our technical brochures are now available for download.
These brochures provide detailed information about our products and their applications.

Technical Data Sheet

Safety Data Sheet

Application Case Studies of HyaSphereX

Product Two-Pager

Certificate of Analysis

Formulation guide

experience the future of bioactive excellence.

Awards

NIA award

The winner of the National Innovation Award 2023. HYN Technology inside HyaSphereX is crowned for its foremost innovation, significantly impacting and driving economic growth.

Tech Planter TH

The winner of the National Innovation Award 2023. HYN Technology inside HyaSphereX is crowned for its foremost innovation, significantly impacting and driving economic growth.

Rohto

The winner of the National Innovation Award 2023. HYN Technology inside HyaSphereX is crowned for its foremost innovation, significantly impacting and driving economic growth.

Glico

The winner of the National Innovation Award 2023. HYN Technology inside HyaSphereX is crowned for its foremost innovation, significantly impacting and driving economic growth.

Innovation Zone Best Ingredient Award

The winner of the National Innovation Award 2023. HYN Technology inside HyaSphereX is crowned for its foremost innovation, significantly impacting and driving economic growth.

NIA award

The winner of the National Innovation Award 2023. HYN Technology inside HyaSphereX is crowned for its foremost innovation, significantly impacting and driving economic growth.

Trusted by

Mizumi Advance Nio-TXB3 Concentrate Serum

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