Simplicity in solutions
Unlocking Skin
WELLNESS
Discover the wonders of HyaSphereX
Discover the wonders of HyaSphereX, where we transform the linear chain of hyaluronic acid into a soft, spherical, 3D nanogel.
unlocking skincare wonders with hyasherex
7 functions
in
1 ingredient
01
Delivery System
Enhance the efficacy with automatically encapsulate, easy, single step, low setup cost
02
Moisturizing
Hydrate the skin, prevent water loss better than hyaluronic acid
03
Soothing
Calm irritate and sensitive skin by reducing COX-2 inflammatory marker
04
Whitening
Reduce number of melanocyte
05
Anti-wrinkle
Reduce wrinkle by inhibit collagenase enzyme, anti-oxidant, prevent cell damage from UV-A exposure.
06
Wound healing
Accelerate wound closure
07
Increase stability
Prevent degradation and color change of vitamin, protein, herbal extracts
How does it work
Promotes efficient uptake by skin cells, maximizing bioavailability and results.
HyaSphereX employs a proprietary mechanism to significantly increase the solubility of bioactive molecules. This breakthrough ensures that these compounds dissolve more readily, paving the way for improved formulations and enhanced therapeutic outcomes.
Facilitates deeper penetration into the skin layers for enhanced efficacy.
Enhance Penetration of Bioactives
HyaSphereX deposits and hydrates epidermis using hydrophobic part that is available on the particle’s surface as a flexible anchor and extremely hydrophilic hyaluronic acid backbone as super-humectant, respectively.
Through the moisturized skin, the very hygroelastic particle of HyaSphereX could squeeze itself with the help of moisture in the extracellular matrix (ECM).
In viable skin layers, underneath stratum corneum, HyaSphereX could be uptaken by keratinocytes and fibroblast derived cells through transcellular and paracellular transportation.
Unique hydrophobic part within swollen HyaSphereX induces the expansion of the very porous particles of HyaSphereX in the deeper skin temperature making hydration even more effective as it excels the accessibility of hydrogen bonds between water and hyaluronic acid backbone.
Prevent Degradation of Bioactives
Both water-soluble and oil-soluble active ingredients can be bonded (non-covalent) with hydrophilic/hydrophobic part of HyaSphereX, possibly hydroxyl groups for hydrophilic polymer/ hydrophobic interaction with hydrophobic crosslink sites. So the degradation is hindered.
Inside the particle is gel matrix meaning that the viscosity is high and molecular motion of water is limited. So it slower the degradation of any molecules.
Enhanced Solubility
HyaSphereX employs a proprietary mechanism to significantly increase the solubility of bioactive molecules. This breakthrough ensures that these compounds dissolve more readily, paving the way for improved formulations and enhanced therapeutic outcomes.Increase Penetration
Our technology goes beyond conventional methods by enhancing the penetration capabilities of bioactive molecules. This means that these compounds can reach their target sites more efficiently, maximizing their impact and potential benefits.
Optimize Cellular Uptake
Promotes efficient uptake by skin cells, maximizing bioavailability and results.
Hydration
HyaSphereX deposits and hydrates epidermis using hydrophobic part that is available on the particle’s surface as a flexible anchor and extremely hydrophilic hyaluronic acid backbone as super-humectant, respectively.
Passive Penetration
Through the moisturized skin, the very hygroelastic particle of HyaSphereX could squeeze itself with the help of moisture in the extracellular matrix (ECM).
Active Cellular Uptake
In viable skin layers, underneath stratum corneum, HyaSphereX could be uptaken by keratinocytes and fibroblast derived cells through transcellular and paracellular transportation.
Hyper-moisturization
Unique hydrophobic part within swollen HyaSphereX induces the expansion of the very porous particles of HyaSphereX in the deeper skin temperature making hydration even more effective as it excels the accessibility of hydrogen bonds between water and hyaluronic acid backbone.
NON-COVALENT INTERACTION
Both water-soluble and oil-soluble active ingredients can be bonded (non-covalent) with hydrophilic/hydrophobic part of HyaSphereX, possibly hydroxyl groups for hydrophilic polymer/ hydrophobic interaction with hydrophobic crosslink sites. So the degradation is hindered.
MINIMIZING THE MOLECULAR MOTION BY SPHERICAL GEL MATRIX
Insdie the particle is gel matrix meaning that the viscosity is high and molecular motion of water is limited. So it slower the degradation of any molecules.
HOW DOES IT WORK
HyaSphereX incorporates multifunctional features, including enhanced solubility, increased penetration, and optimized cellular uptake.
ENHANCE PENETRATION OF BIOACTIVE
HyaSphereX enhances penetration of both water-soluble and oil-soluble active ingredients through transcellular, intercellular, and follicular routes.
PREVENT DEGRADATION OF BIOACTIVE
HyaSphereX, through its unique, flexible 3D nanogel structure, helps increase stability of active ingredient and the formulations.
How does it work
Promotes efficient uptake by skin cells, maximizing bioavailability and results.
Enhances the solubility of active ingredients, ensuring optimal formulation.
Facilitates deeper penetration into the skin layers for enhanced efficacy.
Through the moisturized skin, the very hygroelastic particle of HyaSphereX could squeeze itself with the help of moisture in the extracellular matrix (ECM).
In viable skin layers, underneath stratum corneum, HyaSphereX could be uptaken by keratinocytes and fibroblast derived cells through transcellular and paracellular transportation.
Unique hydrophobic part within swollen HyaSphereX induces the expansion of the very porous particles of HyaSphereX in the deeper skin temperature making hydration even more effective as it excels the accessibility of hydrogen bonds between water and hyaluronic acid backbone.
Both water-soluble and oil-soluble active ingredients can be bonded (non-covalent) with hydrophilic/hydrophobic part of HyaSphereX, possibly hydroxyl groups for hydrophilic polymer/ hydrophobic interaction with hydrophobic crosslink sites. So the degradation is hindered.
Inside the particle is gel matrix meaning that the viscosity is high and molecular motion of water is limited. So it slower the degradation of any molecules.
Enhanced Solubility
HyaSphereX employs a proprietary mechanism to significantly increase the solubility of bioactive molecules. This breakthrough ensures that these compounds dissolve more readily, paving the way for improved formulations and enhanced therapeutic outcomes.Increase Penetration
Our technology goes beyond conventional methods by enhancing the penetration capabilities of bioactive molecules. This means that these compounds can reach their target sites more efficiently, maximizing their impact and potential benefits.
Optimize Cellular Uptake
HyaSphereX facilitates increased cellular uptake of bioactive molecules, ensuring a more efficient and effective interaction with cells. This mechanism enhances the bioavailability of the compounds, amplifying their positive effects within the biological system.
Hydration
HyaSphereX deposits and hydrates epidermis using hydrophobic part that is available on the particle’s surface as a flexible anchor and extremely hydrophilic hyaluronic acid backbone as super-humectant, respectively.
Passive Penetration
Through the moisturized skin, the very hygroelastic particle of HyaSphereX could squeeze itself with the help of moisture in the extracellular matrix (ECM).
Active Cellular Uptake
In viable skin layers, underneath stratum corneum, HyaSphereX could be uptaken by keratinocytes and fibroblast derived cells through transcellular and paracellular transportation.
Hyper-moisturization
Unique hydrophobic part within swollen HyaSphereX induces the expansion of the very porous particles of HyaSphereX in the deeper skin temperature making hydration even more effective as it excels the accessibility of hydrogen bonds between water and hyaluronic acid backbone.
NON-COVALENT INTERACTION
Both water-soluble and oil-soluble active ingredients can be bonded (non-covalent) with hydrophilic/hydrophobic part of HyaSphereX, possibly hydroxyl groups for hydrophilic polymer/ hydrophobic interaction with hydrophobic crosslink sites. So the degradation is hindered.
MINIMIZING THE MOLECULAR MOTION BY SPHERICAL GEL MATRIX
Insdie the particle is gel matrix meaning that the viscosity is high and molecular motion of water is limited. So it slower the degradation of any molecules.
Enhance Penetration of Bioactive
Prevent Degradation of Bioactive
Prevent Degradation of Bioactive
A Glimpse of Amazing Results
Retinol stability was tested in HyaSphereX™ solutions over 7 days at room temperature. Results show that 2-5% w/w of HyaSphereX™ increased stability 1.2-2.5 times compared to a water solution, indicating HyaSphereX™ enhances retinol stability.
To explore HyaSphereX™ solution’s impact on vitamin A-induced inflammation in keratinocytes, cells were pre-treated with HyaSphereX™-Vit A before UVA exposure. Vitamin A notably increased COX-2 expression by 64% compared to UVA alone. However, the addition of 2% HyaSphereX™ solution with vitamin A reduced COX-2 levels post-UVA exposure, indicating potential anti-inflammatory effects.
Nine healthy volunteers applied samples twice daily for 14 days. Results showed 2% Stabilized vitamin C with 1% HyaSphereX™ reduced melanin index 1.3 times more than 2% Stabilized vitamin C alone. Clinical data suggests HyaSphereX™ enhances the whitening effects of vitamin C in skincare products.
ECOCERT COSMOS Approved
Microplastic free
International patented
99.9% Natural origin ISO 16128
HYN Technology Delivery System
Halal
Preservative free
Vegan
Biodegradable
China CosIng
Discover the wonders
These brochures provide detailed information about our products and their applications.
Technical Data Sheet
Safety Data Sheet
Certificate of Analysis
Product Two-Pager
Declaration of Natural Origin
Formulation guide
experience the future of bioactive excellence.
Awards
NIA award
The winner of the National Innovation Award 2023. HYN Technology inside HyaSphereX is crowned for its foremost innovation, significantly impacting and driving economic growth.
Tech Planter TH
The winner of the National Innovation Award 2023. HYN Technology inside HyaSphereX is crowned for its foremost innovation, significantly impacting and driving economic growth.
Rohto
The winner of the National Innovation Award 2023. HYN Technology inside HyaSphereX is crowned for its foremost innovation, significantly impacting and driving economic growth.
Glico
The winner of the National Innovation Award 2023. HYN Technology inside HyaSphereX is crowned for its foremost innovation, significantly impacting and driving economic growth.
Innovation Zone Best Ingredient Award
The winner of the National Innovation Award 2023. HYN Technology inside HyaSphereX is crowned for its foremost innovation, significantly impacting and driving economic growth.
NIA award
The winner of the National Innovation Award 2023. HYN Technology inside HyaSphereX is crowned for its foremost innovation, significantly impacting and driving economic growth.
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